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term vesicles), which supports the needs of the growing fetus, but also in conditions of low maternal Zn consumption or deficiency, which may limit fetal Zn deficiency ( Early studies in artificially perfused human placental lobules, found that tissue Zn concentration was 10 times higher than the concentrations of perfused (plasma) Zn and suggested that transfer of Zn in the syncytiotrophoblast is active, while transfer towards fetal circulation is passive, via simple diffusion ( Interestingly, total fetal Zn (bound and free) in term newborns, as measured in UV via atomic spectrometry, was found to be higher when compared to maternal or amniotic Zn, but free Zn was not significantly different ( The factors that influence the transfer of Zn via the placenta are also not well understood