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Kouroglou E, Anagnostis P, Daponte A, Bargiota A (2019) Vitamin B12 insufficiency is associated with increased risk of gestational diabetes mellitus: a systematic review and meta-analysis

Interestingly, in chronically insulin treated 3T3-L1 cells and fat explants from insulin resistant mice, only insulin-stimulated glucose uptake is decreased while insulin suppression of lipolysis is intact (121), effects which are explained by selective insulin resistance in adipocytes

It is not clear whether the long-term use of H 2 -receptor antagonists could cause overt vitamin B 12 deficiency (141, 142)

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They also support research on biochemical regulation