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(Yale J Biol Med, 2024), Gwyer et al

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The pressure of water can damage the peptide structure

Plan for this by: Timing dose increases to coincide with starting a new vial when possible Calculating remaining doses at the new higher dose before making the switch Having a new vial ready if the dose change will exhaust your current vial sooner than expected Some people choose to split their dose across two weekly injections for better tolerability