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Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes

5-Amino-1MQ functions as a small-molecule inhibitor of NNMT, the enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide

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