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Environmental factors such as pollution, UV exposure, stress, and lifestyle habits can increase oxidative stress levels, which is why antioxidants are an important area of interest in skin health

Acknowledgements This research was supported by a grant from Tehran University of Medical Science

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The solution obtained was then centrifuged at 1000 g for 10 min at 4 C, and the supernatant was filtered through a 0.2-m nylon syringe filter for subsequent HPLC analysis 28