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Inhibition of phosphofructokinase-1 will lead to a buildup of fructose-6-phosphate and glucose-6-phosphate, and the latter will further allosterically inhibit hexokinase

10.1126/science.286.5440.735 152 ViswanathanJ.HaapasaloA.BttcherC.MiettinenR.KurkinenK

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Autophagy and mitophagy maintain oxygen balance by degrading dysfunctional mitochondria and preventing excessive accumulation of ROS

While it is important to acknowledge the occurrence of rare autoimmune events such as Graves disease following COVID-19 vaccination, these cases should be interpreted within the broader context of vaccine safety and global benefit

This allows the nutrient to be delivered directly to the cells that need it most