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But BDNF is not only a brain molecule

However, the effectiveness of traditional treatment methods for osteosarcoma is still limited, as the 5-year survival rate falls within the range of 60% to 70%

Hellinger R, Sigurdsson A, Wu W, Romanova EV, Li L, Sweedler JV

Nature Communications (2018) 2

it is supplied as a chemical reagent for laboratory use

Clinical translational research shows that in a Phase II clinical trial of newly diagnosed high-risk diffuse large B-cell lymphoma (DLBCL) (n=100), oral HDAC inhibitor Tucidinostat (20 mg per dose) in combination with the R-CHOP regimen achieved an 86% complete response rate (91)