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This article summarises the research literature on each, identifies the structural and mechanistic differences, and outlines what the research community is currently studying

For instance, SIRT1 alters the acetylation patterns of histones H3 and H4, including H3k4ac, H3k9ac and H4k16ac, to regulate the expression of cancer-related genes in breast cancer

Chen L, Min J, Wang F

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The rationale for their use in our investigation include the demonstration of androgen responsive genes associated with oxidative stress 10

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