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Without direct comparison studies, precise translation remains impossible

Crossbreeding of UCHL-eGFP with prpTDP-43 A315T mouse model of ALS, generated prpTDP-43 A315T -UeGFP mice (diseased) and WT-UeGFP mice (healthy control)

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In vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy