Vitamin B12 fosters red blood cell formation, aids in nerve function, the metabolism of the cells, and the creation of DNA
NNMT participates in nicotinamide metabolism through this activity
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In mouse models of highfat dietinduced liver steatosis, it significantly inhibits hepatic NNMT activity, reduces NAM methylation, increases NAD+ and SAM levels, enhances mitochondrial fatty acid oxidation, reduces hepatic triglyceride and lipid accumulation, lowers lipotoxicity markers (e.g., malondialdehyde, transaminases), improves hepatocellular injury, and reverses steatosis
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Also known as cobalamin, it is a water-soluble vitamin essential for neurological function and DNA synthesis