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Metformin inhibits growth of thyroid carcinoma cells, suppresses self-renewal of derived cancer stem cells, and potentiates the effect of chemotherapeutic agents
It varies by individual and treatment
Ultimately, these data should inform biomarker-enriched, early-phase clinical trials that co-stratify patients by pathway activity and genomic alterations, thereby accelerating the development of precision therapies for women with EAOC
Toxicol Appl Pharmacol 204:329342 Sun X, Shih AY, Johannssen HC, Erb H, Li P, Murphy TH (2006) Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface
One of the enzymes involved in the process of converting pyruvate, which is derived from glucose, into energy in the form of ATP inside of the mitochondria
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