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Hyperglycemia-induced reactive oxygen species and impaired endothelial progenitor cell function

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The manuscript is read and approved by all the authors

In this work, we comprehensively summarize the latest research on the pathogenesis and diagnosis of MDD, preventive approaches and therapeutic medicines, as well as the related clinical trials

A scientific review published in the National Library of Medicine in 2022 found that nose-to-brain delivery of therapeutic peptides is a non-invasive and fast-acting method that can effectively bypass the blood-brain barrier while minimizing systemic exposure