It hosts an exceptionally dense microbial population (10 11 cells/mL), dominated by bacteria but also including archaea, protozoa, and anaerobic fungi, a composition distinct from monogastric systems (Table 1)
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Although saikosaponins have poor intestinal absorption due to their large molecular mass, high molecular flexibility, and high hydrogen-bonding capacityfeatures that limit membrane permeabilitycertain subtypes (saikosaponin a, b1, d, g, c) have been shown to exhibit relatively high bloodbrain barrier permeability in a microdialysis experiment, making them potential antidepressants (Yu et al., 2012
Additionally, paraxanthine may boost cognitive function across age groups by increasing BDNF levels
The hormonal mechanism of the effects of meperidine, sertraline, tianeptine, and their combinations on reproductive functions in female rats
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