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Although the circulating creatinine concentration and creatinine clearance are normal, the urinary albumin/creatinine ratio of such rats is high, suggesting a loss of the glomerular filtration barrier, rather than a loss of renal function

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Morrison N, Gibson K, Vasquez M, Weiss R, Cher D, Madsen M, Jones A

Pyo et al., 2021)

Reduced-dose maintenance is better supported than complete withdrawal, but the exact interval remains uncertain