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Daily injections at the beginning are key for: Quickly fixing the deficiency Reducing severe symptoms Getting ready for ongoing treatment Secondary Phase: Weekly Injections for One Month After the first week, injections are given weekly for a month

These include water retention, joint discomfort, or changes in blood sugar regulation

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declares having received consulting honoraria from Novo Nordisk, Eli Lilly, Boehringer Ingelheim and AstraZeneca, and received research grants through his affiliation from Novo Nordisk, Eli Lilly, Boehringer Ingelheim and Rhythm

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Biochemical Pharmacology, 147, 141152