A 2022 paper from Stanford University identified six manufacturers of synthetic nicotine and 98 brands claiming to contain synthetic nicotine
The CDC advises that people do not use e-cigarettes or vaping products containing THC from non-regulated markets including friends, family, or in person or online dealers
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1 Tobacco smoke contains carbon monoxide, which displaces the oxygen in your blood, meaning your major organs arent getting the oxygen that they need to function properly
They do contain tar, but its minimal compared to real cigarettes