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[DOI] [PubMed] [Google Scholar] 12.Smelser N.J., Baltes P.B

The specific reactivity of each NAC thiol is governed by its micro and macro-environment in the solution, with its pKa and redox potential influenced by the local polarity and interactions with neighboring residues

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Upstream regulatory pathways and transcription factors p53 pathway p53 is a master stress-responsive transcription factor that governs cell-cycle arrest, senescence and apoptosis, and its functional inactivation represents a central event in tumorigenesis