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Research with NNMT blockers such as 5-amino-1MQ has demonstrated increased GLUT4 expression, greater glucose utilization, and enhanced metabolic activity

Some practitioners prefer it because of this, arguing that patients with certain metabolic variants may convert cyanocobalamin less efficiently

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B12 is primarily found in animal-based foods such as meat, dairy, and eggs, and is absorbed in the small intestine after binding to a protein

Aim for 0.3-0.5g per pound of body weight

AOD9604 had a very short half-life of only approximately 3 min after IV injection