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Both PGE2 and PGI2 are pro-inflammatory prostanoids that increase vascular permeability, promote leukocyte infiltration and increase edema formation 4

PMID: 11909872

Consequently, this imbalance results in damage to hippocampal neurons which can trigger or exacerbate depression

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Fucoidan enhanced the functioning of mitochondria and protected the brain by actively controlling the Nrf2 pathway

As discussed previously, these proposals for the LTCH QRP will result in an overall decrease in burden for LTCHs, and we believe the importance of the information necessitates these provisions