1 2 European Journal of Organic Chemistry
The improvements seen in people with megaloblastic anemia dont apply to those with normal B12 levels
This hypothesis is supported by several studies that have shown supplementation with SAM improves depressive symptoms (104-107)
The UK-wide survey, which ran between June 26, 2020, and October 5, 2020, fielded 683 responses
(PubMed) Shaw GM, Carmichael SL, Yang W, Selvin S, Schaffer DM
Common examples include fatigue or low energy with normal blood results, brain fog or reduced concentration without confirmed vitamin B12 deficiency, stress-related exhaustion or burnout, increased metabolic demand such as during illness recovery, high workload, or intense training, restrictive or inconsistent dietary intake, or suspected poor oral absorption despite normal serum levels