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Additionally, in aging rats, Rab GTPases were reported to be involved in exocytosis of tear components, and antioxidant markers were found to be decreased [80]

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

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Together these results suggested that this antiretroviral therapy compromises the BBB and could be associated with HIV-1 neurological diseases

Although not much is known about these enzymes in cancer, the CHAC2 isoform has already been classified as a tumour suppressor gene in gastric and colorectal cancer, on the basis of its downregulation being associated with more aggressive cancer variants and its activation-inducing apoptosis in cancer cells