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Physical Withdrawal Symptoms Cravings for nicotine Irritability Difficulty concentrating Increased appetite Weeks 3-4: Psychological Adjustments In weeks 3-4 of nicotine addiction recovery, individuals may experience psychological adjustments as they adapt to life without nicotine

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Consult a healthcare provider if symptoms worsen

After cigarette smoking, nicotine quickly acts on its target, nicotinic acetylcholine receptors (nAChRs), which are widely distributed throughout the mammalian central nervous system and are expressed as diverse subtypes on cell bodies, dendrites and/or nerve terminals

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