In general, under physiological conditions, substances can cross the BBB through five pathways, including passive diffusion, carrier-mediated transport, adsorptive-mediated transcytosis, adsorptive-mediated transcytosis, and efflux pumps[31, 32] (Fig
2.14 Kunming mice insights into Alzheimers disease research Kunming mice, closely related to the C57BL strain, are highly valued in AD research for their resilience, adaptability, and high reproductive efficiency
Lack of NLRP3-inflammasome leads to gut-liver axis derangement, gut dysbiosis and a worsened phenotype in a mouse model of NAFLD
The tripeptide consists of the amino acids glutamic acid, cysteine and glycine
These corrected data were then used for the analysis and are included in Supplementary Table 6
81 Additionally, CB2R knockout mice exhibit gut flora dysbiosis similar to that of NAFLD patients and model mice