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A ketogenic diet alone had variable effects in the different tumor models used in the study, the researchers wrote, indicating that the dietary changes themselves were insufficient to cause the tumor responses observed. In fact, in a mouse model of leukemia, the diet appeared to accelerate cancer progression

414 Very similar effects were caused by inhibiting glial glutamate transporters in the prefrontal cortex

In addition, a persistent inflammatory state triggers a sharp increase in oxidative stress levels in thyroid tissue and the production of excessive reactive oxygen species (ROS)

Transplantation 56, 709716