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135 Dihydroartemisinin can significantly inhibit the viability of leukemia cells, causing cell cycle G0/G1 phase arrest and ferroptosis, and the mechanism may be related to inducing autophagy and accelerating ferritin degradation by regulating AMP-activated kinase (AMPK)/mTOR/p70S6k signaling pathway
Although the two GCL subunits are coordinately up-regulated by many inducers of oxidative stress and treatment with antioxidants (Galloway et al., 1997
Menthapiperita , native to Asia and Europe (372), is commonly used as a flavoring agent (373, 374)
Tochigi M, et al
Toxicol in Vitro
Overall, our results propose a novel therapeutic strategy for APAP-induced liver injury, involving hepsin administration alongside a low dose of NAC to improve treatment effectiveness and address current limitations
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