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While these nutrients have shown depigmentation effect on skin in initial studies, further large-scale human trials are needed for confirmation of these effects of specific food items

10.1111/prd.12254 33 GuoJ.RenR.SunK.YaoX.LinJ.WangG.et al (2020)

Mediation of endogenous antioxidant enzymes and apoptotic signaling by resveratrol following muscle disuse in the gastrocnemius muscles of young and old rats

It can take years for a deficiency to develop in the first place

Activation of the NF-B pathway leads to the inflammatory EC responses by chemokines release, such as macrophage chemoattractant protein-1 (MCP-1) and IL-8 (50)

Blood 144 , 347348 (2024)