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On the basis of the biological plausibility and anecdotal case reports of clinical improvement, (in)GSH has been recommended as an off-label therapy for GSH augmentation in PD since 2004

Informed consent was obtained from all enrolled participants in the study

Chechowska M, Gajewska J, Szczepanik E, Mazur J, Cychol A, Kuniar-Paka A, Ambroszkiewicz J (2025) Oxidative stress indicated by nuclear transcription factor Nrf2 and glutathione status in the blood of young children with autism spectrum disorder: pilot study

Constantino IC, Bento LR, Santos VS et al (2024) Seasonal studies of aquatic humic substances from Amazon rivers: characterization and interaction with Cu (II), Fe (II), and Al (III) using EEM-PARAFAC and 2D FTIR correlation analyses

Synthetic peptide production and strict quality control systems allow consistent dosing, but the legal classification of peptides as drugs, supplements, or biologics differs from one jurisdiction to another

We also observed a reduction in IL-6 expression and an increase in IL-8 expression after FOXO4-DRI treatment