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A new therapeutic effect of simvastatin revealed by functional improvement in muscular dystrophy

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Acute lung injury models in mice demonstrate reduced inflammatory cell infiltration, increased superoxide dismutase activity, and decreased TNF- and IL-6 production

On the fourth day, the mice were euthanized, lungs were dissected and digested to produce single-cell suspensions as previously described

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PLoS One 9:e92626 Furuyama T, Kitayama K, Shimoda Y, Ogawa M, Sone K, Yoshida-Araki K, Hisatsune H, Nishikawa S, Nakayama K, Nakayama K, Ikeda K, Motoyama N, Mori N (2004) Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice