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it was studied by Novo Nordisk and later Helsinn Therapeutics, including a Phase II trial for postoperative ileus, but development was discontinued for lack of efficacy

Candidalysin is required for neutrophil recruitment and virulence during systemic candida albicans infection

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When the gut environment is calm, vagal tone improves, shifting the autonomic nervous system away from the hyper-aroused "fight or flight" sympathetic state and toward the restorative "rest and digest" parasympathetic state

Zhao L, Guo J, Xu S,Duan M, Liu B,Zhao H,Wang Y, Jiang X, Jiang X