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The p38 signal transduction pathway: activation and function

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10.1038/s41596-018-0119-1 61

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In addition, in PC12 and N2a cells, low-concentration administration of berberine significantly reduced the amount of ROS generation, lipid peroxidation, and DNA fragmentation, and at the same time increased glutathione content and superoxide dismutase activity (Sadeghnia et al., 2017)