Intriguingly, the emerging trained immunity may provide a possible explanation for non-specific effects
It does not necessarily lead to a significantly lighter skin tone in everyone
NAFLD, nonalcoholic fatty liver disease
J Am Nutr Assoc 44(5):375386 Kuptniratsaikul V, Dajpratham P, Taechaarpornkul W, Buntragulpoontawee M, Lukkanapichonchut P, Chootip C, Saengsuwan J, Tantayakom K, Laongpech S (2014) Efficacy and safety of Curcuma domestica extracts compared with ibuprofen in patients with knee osteoarthritis: a multicenter study
PT-141 (Bremelanotide) A peptide derived from melanotan that stimulates the melanocortin receptor pathway
Curculigoside has been reported to downregulate Beclin-1 expression and the LC3-II/I ratio, potentially reducing autophagy-related damage (Meng et al., 2024)