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Together, these data support a model in which adoptively transferred splenocytes from aged mice initiate a systemic inflammatory cascade, which in turn activates and expands endogenous tissue-resident macrophages, leading to sustained tissue functional impairment

Wakabayashi, K

Moreover, we outline therapies aimed at various mitochondrial dysfunctions, highlighting their performance in animal models and human trials

60 Intravenous (IV) therapy with glutathione and antioxidants represents an advanced and targeted approach to promoting health and well-being

By enriching our understanding of protein degradation, we can begin to formulate strategies to treat neurodegenerative diseases remediating aspects of UPS dysregulation