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A randomized, double-blind, placebo-controlled trial in 153 older adults taking the antidepressant citalopram found daily supplementation with 500 g vitamin B 12 , 2 mg of folic acid, and 25 mg of vitamin B6 for one year did not reduce the severity of depressive symptoms but increased the response to drug treatment and helped to prevent symptom relapse (112), suggesting B-vitamin supplementation might provide some benefit as an adjunct therapy

B12 injections can prevent and even reverse some of these symptoms

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AOD9604 has been studied in preclinical and early clinical settings, and it received GRAS (Generally Recognized as Safe) designation from the US FDA for use as a food ingredient

Additional Safety Information: Not recommended for individuals who are pregnant, breastfeeding, or planning to become pregnant or breastfeed

CL Answer Do essential amino acid (EAA) supplements help build muscle better than dietary protein or protein supplements