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Increase to 1mg daily and extend the evaluation window to 16 weeks

Furthermore, ER stress has been reported to induce EMT 50

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This protective mechanism potentially contributes to cell survival in normal cells.Another study by Boubaker et al

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however, when handled as a research chemical: Effects are dependent on concentration, exposure conditions, and experimental model High concentrations in vitro may alter cellular redox balance and produce unintended experimental outcomes Long-term effects in experimental systems depend on study design and conditions Handling Precautions: Use appropriate personal protective equipment (PPE) including gloves, lab coat, and eye protection Avoid inhalation, ingestion, or direct contact with skin and eyes Handle under controlled laboratory conditions using standard safety protocols Regulatory Status: Not approved by the U.S