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In rabbits, resorptions, decreased litter size, and decreased fetal weights were observed at maternally toxic doses, at systemic exposures greater than 8 times higher than exposure at the approved human dose of PAXLOVID

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A CP with one or two RPs can be found in the proteasome, resulting in the asymmetric 26S proteasome or 30S proteasome, respectively[14]

Liu J, Chu M, Zhang J, et al