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Further supporting the mitochondrial protection paradigm, Kuntai Capsule, a TCM-based formulation, alleviates POI by activating the FOXO3/SIRT5 signalling pathway, enhancing mitochondrial biogenesis and reducing apoptotic cell death [166]

The model shows that overexpression of genes on chromosome 21 and an increase in oxidative stress can explain the metabolic profile of Down syndrome

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Injection site reactions including temporary redness, swelling, or discomfort occur occasionally