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ACO is currently primarily defined as persistent airflow limitation with several features commonly associated with asthma and several features commonly associated with COPD 47,48

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J Am Coll Cardiol 67(23):28022803 Farsalinos KE, Spyrou A, Tsimopoulou K, Stefopoulos C, Romagna G, Voudris V (2014) Nicotine absorption from electronic cigarette use: comparison between first and new-generation devices