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The strong oxidative properties of O can damage cell membranes, proteins, and DNA, leading to oxidative stress and inflammatory responses that may result in respiratory symptoms as well as chronic respiratory diseases [91]

Hirai, N

Covalent/irreversible inhibitors target the redox/catalytic apparatus of TGR with almost no recognition elements that give affinity and selectivity for TGR over off-targets and the cellular redox apparatus resulting in undesirable cross-reactions and low specificity in vivo 25

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10.1016/j.bbamem.2018.02.020 6 AtkinsonJ

In addition to delivering pro-angiogenic molecules, vascular networks can be physically engineered to induce blood perfusion from the host tissue to the implant and to promote monocyte function with pro-angiogenic properties (Lee et al., 2020)