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The TYR gene, involved in melanin biosynthesis in melanocytes, has been significantly associated with vitiligo in the European population.63 The roles of many susceptibility loci remain unknown, highlighting the lack of understanding in the etiopathogenesis of vitiligo, which continues to be a challenge today

PMID 29167919

Since taking lipoic acid with a meal decreases its bioavailability, it is generally recommended that lipoic acid be taken 30 min prior to a meal (see also Metabolism and Bioavailability) (8)

It is also associated with improved skin health, as it may help reduce the appearance of hyperpigmentation and promote a more radiant complexion

Jan-Mar 2002;6(1):65-68

Take it in the morning and midday, ideally on an empty stomach