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In particular, the precise regulatory interactions between MGST3 and key signaling pathways, such as the NRF2/GPX4 axis or lipid metabolic remodeling networks, require further detailed investigation

The MELK inhibitor OTSSP167 protects intestinal epithelial cells by maintaining a normal composition of gut microbiota and balancing gut microbiota distribution, inhibiting ferroptosis, reducing the expression of pro-inflammatory factors in intestinal tissues, and suppressing the AKT/IKK/P65 and ERK/IKK/P65 signaling cascades in vitro and in vivo, thereby exerting a protective effect on the intestinal tissues of colitis mice [291, 292]

Acetaminophen toxicity, more common in women than men, is most common in people aged 30-40 years

Eluri M, Sun R, Bubie A, Alshenaifi J, Zhang N, Drusbosky L, Parseghian CM, Singh Raghav KP, Kopetz S

International Journal for Vitamin and Nutrition Research

Khorram, O., Laughlin, G