But clearly I think what the study showed was that this is a practice that's probably happening more often in Ontario than it should be happening." Silverstein, a recent graduate of medical school, remembered that little time was spent on the appropriate treatment of B12 deficiency
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In the presence of neurological symptoms, following daily treatment, injections up to weekly or biweekly are indicated for six months before initiating monthly IM injections
However, it is important to note that there is no established direct mechanism by which tirzepatide interferes with B12 absorption or metabolism
A 2025 meta-analysis of 16 studies involving 6,098 participants found no statistically significant difference between intramuscular, oral, and sublingual B12 supplementation routes (p=0.270)
Malignancy: Oncology referral for appropriate cancer treatment (surgery, chemotherapy, radiotherapy)
