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Runners knee is normally caused by irritation of the soft tissues or lining of the knee or by strained tendons or worn cartilage

doi: 10.1146/annurev.immunol.23.021704.115653 12 FriedmanAD

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That accident if you want to call it that launched fifty years of research across wound healing, collagen biology, gene expression, and a half-dozen other fields that werent even on anyones radar at the time

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Then, 100 L of TMB solution and 100 L of H 2 O 2 (10 mM) in dimethyl sulfoxide (2 mM) were added to the NP solutions