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Results demonstrated significant improvements in sleep efficiency and subjective sleep quality ratings in the DSIP treatment group, with particular enhancement of the first sleep cycle and improved transition into slow-wave sleep

Animal studies have also found that intermittent fasting lowers IGF-1 more effectively than long-term calorie restriction, but other studies have found no difference between the two (32, 33)

10.1146/annurev.neuro.24.1.1121 Annu

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Molecular mechanism of platelet-derived growth factor (PDGF)-BB-mediated protection against MPP(+) toxicity in SH-SY5Y cells

And if you are coming from semaglutide rather than injectable tirzepatide, the semaglutide to tirzepatide conversion chart is the starting reference before applying the sublingual bioavailability adjustment