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For patients with metabolic syndrome, the combination of CoQ 10 and red yeast rice provided benefits to their blood pressure, lipid, and glycemic biomarkers in another 2018 RCT [195]

A high-sucrose, high-fat diet causes harmful oxidative modification in metabolically active proteins, resulting in maladaptive tissue remodeling and potentially exacerbating diastolic left ventricular dysfunction

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The in vitro environment subjects gametes and embryos to an abundance of ROS in the absence of enzymatic antioxidant defenses that are normally present during in vivo fertilization and pregnancy