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Cauda equina syndrome: If you experience sudden onset of bowel or bladder dysfunction, bilateral leg weakness, or saddle anesthesia (numbness in the groin and inner thighs), this is a surgical emergency

Follow standard reconstitution and storage protocols

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In those patients, addressing the underlying metabolic dysfunction first, through dietary intervention, GLP-1 therapy if indicated, or NAD+ support for cellular energy metabolism, is the clinical priority

Derwa Y, Gracie DJ, Hamlin PJ, Ford AC