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IGF is a central player in changing the fate of cells during survival and proliferation through the modulation of leading signaling pathways, including Jak/STAT, MAP kinase/ERK, and PI3K/Akt, and subsequent impacts on steroidogenesis and cell division

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( Quantification of a Panel of Inflammatory Cytokines The levels of the anti-inflammatory cytokine IL-10 and the pro-inflammatory cytokines TNF-, IL-6, and IL-1 in brain cell homogenates were quantified using specific ELISA kits (Ray Biotech, Peachtree Corners, GA, USA) according to the manufacturers instructions

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