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The dendritic cells and macrophages are responsible for producing cytokines such as TGF-, IL-6, IL-1b, IL-23, and IL-21, which provide an environment for differentiation of Th17 and suppress the differentiation of regulatory T cells (Genovese et al

VEGF, Vascular endothelial growth factor

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For instance, exo-metabolomics of conditioned media from monocultures and co-cultures could reveal metabolite utilization and production profiles of these microbes, hence inferring the extent of resource competition and cross-feeding (Venturelli et al., 2018

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