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Methods: UC was induced in BALB/c mice with 3% DSS for 14 days

In hypertensive states, mitochondria generate excessive ROS due to electron transport chain (ETC) disruption, particularly at complexes I and III, coupled with reduced antioxidant defenses (e.g., Mn-SOD) (Grossini et al., 2025)

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Doxycycline shows favorable intra-cellular penetration, with bacteriostatic activity on a wide range of bacteria

By incorporating glutathione and other bioactive compounds, you will enjoy a comprehensive solution to improve the health and productivity of crops and thus reduce the negative effects caused by different causes of abiotic stress