In all cases, the selected and analysed areas were normalised to the number of total pixels selected and the blue channel was used as the threshold to remove the background from hematoxylin staining and orange and red were used to calculate positive pixel density based on the following formula: Iron measurement of human brain tissue Brain tissue was obtained from the NeuroBiobank of the Institute Born-Bunge (NBB-IBB), Wilrijk (Antwerp), Belgium (ID: BB190113), and donors gave informed consent to donate their brains to the NBB-IBB
10.1080/0886022x.2016.1209380 76 XueG
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The expression of GPX3 can inhibit the activation of NF-B through the Erk pathway, leading to the suppression of the cell cycle proteins B1 and G2/M and the inhibition of epithelial-mesenchymal transition (EMT) by downregulating the Erk-NF- B-SIP 1 signaling axis (40)
