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This work is supported by Key R&D Program of China National Tobacco Corporation (110202202019)

Antioxidant Defense: Glutathione helps maintain the redox state within cells, which is vital for cellular health

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Contributing to inflammation and redness, it is also possible that the loss of IGF-1 may increase inflammation since IGF-I inhibits actions on inflammatory and Th1-mediated cellular immune responses through stimulation of IL-10 production in T cells